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Refining Genetically Inferred Relationships Using Treelet Covariance Smoothing
covariance estimation cryptic relatedness genome-wide associ-ation heritability kinship.
2012/9/17
Recent technological advances coupled with large sample sets have un-covered many factors underlying the genetic basis of traits and the predis-position to complex disease, but much is left to discove...
Smoothing ℓ₁-penalized estimators for high-dimensional time-course data
Lasso Local least squares Multivariate regression Variable selection Weighted likelihood
2009/9/16
When a series of (related) linear models has to be estimated it is often appropriate to combine the different data-sets to construct more efficient estimators. We use ℓ₁-penalized estimato...
Extensions of smoothing via taut strings
conditional means conditional quantiles modality penalization uniform consistency total variation tube method
2009/9/16
Suppose that we observe independent random pairs $(X_1,Y_1)$, $(X_2,Y_2)$, ..., $(X_n,Y_n)$. Our goal is to estimate regression functions such as the conditional mean or $beta$--quantile of $Y$ given ...