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Simultaneous expansion and harvest of hematopoietic stem cells and mesenchymal stem cells derived from umbilical cord blood
生物反应器 UCB MSCs RWV GCSC
2023/3/1
The simultaneous expansion and harvest of hematopoietic stem cells and mesenchymal stem cells derived from umbilical cord blood were carried out using bioreactors. The co-culture of umbilical cord blo...
Prenatal Maternal Physical Activity and Stem Cells in Umbilical Cord Blood
REAST STEM CELLS CARDIOVASCULAR FITNESS EARLY LIFE DETERMINANTS
2017/4/13
Purpose: Early life processes, through influence on fetal stem cells, affect postnatal and adult health outcomes. This study examines the effects of physical activity before and during pregnancy on st...
Effects of Extracellular Matrix Protein-derived Signaling on the Maintenance of the Undifferentiated State of Spermatogonial Stem Cells from Porcine Neonatal Testis
Porcine Spermatogonial Stem Cells Undifferentiation, Extracellular Matrix Proteins
2016/11/10
In general, the seminiferous tubule basement membrane (STBM), comprising laminin, collagen IV, perlecan, and entactin, plays an important role in self-renewal and spermatogenesis of spermatogonial ste...
Isolation and Identification of Prepubertal Buffalo (Bubalus bubalis) Spermatogonial Stem Cells
Buffalo Spermatogonial Stem Cell Germ Cell Marker Proliferation
2016/11/10
Isolation and culture of spermatogonial stem cells (SSCs) are attractive for production of genetic modified offspring. In the present study, buffalo spermatogonial stem-like cells were isolated, cultu...
FUNCTIONAL GENOMICS STUDY TO UNDERSTAND THE ROLE OF SEROTONIN IN MOUSE EMBRYONIC STEM CELLS
Serotonin mouse embryonic stem cells
2015/5/26
Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine neurotransmitter that is synthesized from the amino acid L-tryptophan and is reported to localize in mitochondria of embryonic stem cells. Even bef...
Derivation of endothelial colony forming cells from human cord blood and embryonic stem cells
Embryonic Stem Cells Directed Differentiation Human Umbilical Cord Blood
2015/5/25
Endothelial Colony Forming Cells (ECFCs) are highly proliferative endothelial progenitor cells with clonal proliferative potential and in vivo vessel forming ability. While endothelial cells have been...
Tsg-6 : an inducible mediator of paracrine anti-inflammatory and myeloprotective effects of adipose stem cells
Adipose stem cell inflammation TSG-6 hematopoiesis smoking
2015/5/22
Tumor necrosis factor-induced protein 6 (TSG-6) has been shown to mitigate inflammation. Its presence in the secretome of adipose stem / stromal cells (ASC) and its role in activities of ASC have been...
Reconstitution of mouse inner ear sensory development from pluripotent stem cells
Inner ear Pluripotent stem cells Hair cells
2015/5/21
The inner ear contains specialized sensory epithelia that detect head movements, gravity and sound. Hearing loss and imbalance are primarily caused by degeneration of the mechanosensitive hair cells i...
Characterization of Bovine NANOG5′-flanking Region during Differentiation of Mouse Embryonic Stem Cells
Bovine Embryonic Stem Cell NANOG Promoter Neural Differentiation Adipocyte Differentiation
2016/5/19
Embryonic stem cells (ESCs) have been used as a powerful tool for research including gene manipulated animal models and the study of developmental gene regulation. Among the critical regulatory factor...
Mesenchymal Stem Cells Augment the Adaptive Response to Eccentric Exercise
A7 INTEGRIN SATELLITE CELLS STEM CELL ANTIGEN-1 DOWNHILL RUNNING REPAIR GROWTH
2017/4/14
Purpose: The α7β1 integrin is a transmembrane protein expressed in the skeletal muscle that can link the actin cytoskeleton to the surrounding basal lamina. We have previously demonstrated that transg...
Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain
APE1 DNA repair hematopoiesis
2014/12/12
Ape1 is a molecule with dual functions in DNA repair and redox regulation of transcription factors. In Ape1-deficient mice, embryos do not survive beyond embryonic day 9, indicating that this molecule...
Analysis of differentiation capacity of Cfp1 null embyronic stem cells
Stem Cells Cell Differentiation Epigenetics DNA Methylation Mice Cardiomyocytes Neurons Leukemia Inhibitory Factor
2015/5/22
Epigenetics is defined as “the study of stable, often heritable, changes that influence gene expression that are not mediated by DNA sequence” (Fingerman et al., 2013). Epigenetic marks such as covale...
Does DNA Methylation Plays a Critical Role in Osteoblastic Differentiation of Mesenchymal Stem Cells (MSCs)?
Mesenchymal Stromal Cells Cell Differentiation Osteoblastic
2015/10/8
Mesenchymal stem cells (MSCs) are characterized by ability to differentiate into several cell types and self-renewability. These stem cells have a limited capacity in cell lineage differentiation incl...
Transcriptional Regulation of Retinal Progenitor Cells Derived from Human Induced Pluripotent Stem Cells.
Stem Cell Human iPS Differentiation Development Retina
2015/5/22
In order to develop effective cures for diseases and decipher disease pathology, the need exists to cultivate a better understanding of human development. Existing studies employ the use of animal mod...
The Use of Blood Vessel–Derived Stem Cells for Meniscal Regeneration and Repair
MENISCUS MENISCAL TEAR VASCULAR AVASCULAR, MULTILINEAGE DIFFERENTIATION
2017/7/17
Purpose: Surgical repairs of tears in the vascular region of the meniscus usually heal better than repairs performed in the avascular region; thus, we hypothesized that this region might possess a ric...