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De novo lipogenesis during controlled overfeeding with sucrose or glucose in lean and obese women
De novo lipogenesis deuterium overfeeding
2016/6/14
The results of previous studies suggest that de novo
lipogenesis may play an important role in the etiology of obesity,
particularly during overconsumption of different carbohydrates.
No common energy currency: de novo lipogenesis as the road less traveled
lipogenesis energy currency
2016/6/14
Bees make wax (lipid) from honey (carbohydrate). Pigs fatten
on a grain diet. Indeed, all organisms, from bacteria to mammals,
have the enzymes of de novo lipogenesis. The physiologic
function of d...
Postprandial de novo lipogenesis and metabolic changes induced by a high-carbohydrate, low-fat meal in lean and overweight men
Obesity hyperinsulinemia carbohydrates
2016/6/12
Adjustments of carbohydrate intake and oxidation
occur in both normal-weight and overweight individuals. Nevertheless,
the contribution of carbohydrates to the accumulation of
fat through either re...
De novo lipogenesis, lipid kinetics, and whole-body lipid balances in humans after acute alcohol consumption
lipolysis hypertriglyceridemia acetate
2016/6/2
Acute alcohol intake is associated with changes in
plasma lipid concentrations and whole-body lipid balances in
humans. The quantitative roles of hepatic de novo lipogenesis
(DNL) and plasma acetat...
Effects of indole-3-carbinol on metabolic parameters and on lipogenesis and lipolysis in adipocytes 182
indole-3-carbinol lipid metabolism rat
2015/6/8
Indole-3-carbinol (I3C) was found to have possible anticarcinogenic, antioxidant and anti-atherogenic effects on the organism. So far, its influence on metabolic pathways has been unknown. This work w...
Palmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis
palmitoleic fatty acid VLDL triacylglycerol biomarker lipogenesis stearoyl-CoA desaturase
2018/12/19
Background: Biochemical evidence has linked the coordinate control of fatty acid (FA) synthesis with the activity of stearoyl-CoA desaturase-1 (SCD1). The ratio of 16:1n–7 to 16:0 [SCD1(16)] in plasma...
Prospective association of fatty acids in the de novo lipogenesis pathway with risk of type 2 diabetes: the Cardiovascular Health Study
diabetes mellitus fatty acids metabolism biomarker diet
2018/12/20
Background: Experimental evidence suggests that hepatic de novo lipogenesis (DNL) affects insulin homeostasis via synthesis of saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs). Few...
Supplementation Effects of C18:2 or C18:3 Rich-oils on Formations of CLA and TVA, and Lipogenesis in Adipose Tissues of Sheep
Conjugated Linoleic Acid Oils Lipogenesis Lipogenic Enzymes Adipose Tissue Sheep
2016/5/3
The present study was conducted to investigate the supplementation effects of C18:2 rich-soybean oil or C18:3 rich-perilla oil (7% of total diet, DM basis) for 12 weeks on plasma metabolites, fatty ac...
Effect of Overfeeding on Plasma Parameters and mRNA Expression of Genes Associated with Hepatic Lipogenesis in Geese
Fatty Liver Goose Lipids Overfeeding Hepatic Lipogenesis
2016/4/27
The aim of our study was to research the effect of overfeeding on plasma parameters and mRNA expression of genes associated with hepatic lipogenesis in the Sichuan white goose and Landes goose. Fifty-...
Consumption of resistant starch decreases postprandial lipogenesis in white adipose tissue of the rat
white adipose tissue rat
2008/4/23
Chronic consumption of diets high in resistant starch (RS) leads to reduced fat cell size compared to diets high in digestible starch (DS) in rats and increases total and meal fat oxidation in humans....
Supplementation Effects of C18:2 or C18:3 Rich-oils on Formations of CLA and TVA, and Lipogenesis in Adipose Tissues of Sheep
Conjugated Linoleic Acid Oils Lipogenesis Lipogenic Enzymes Adipose Tissue Sheep
2016/4/26
The present study was conducted to investigate the supplementation effects of C18:2 rich-soybean oil or C18:3 rich-perilla oil (7% of total diet, DM basis) for 12 weeks on plasma metabolites, fatty ac...
Effects of Zinc on Lipogenesis of Bovine Intramuscular Adipocytes
Zinc Intramuscular Adipocytes Bovine PPAR 2 Nitric Oxide
2016/4/18
Zinc (Zn) is a micromineral and functions as a cofactor of many enzymes and its deficiency induces retardation of growth and dysfunction of the immune system in animals. This study was conducted to de...
Addition of inulin to a moderately high-carbohydrate diet reduces hepatic lipogenesis and plasma triacylglycerol concentrations in humans
Inulin stable isotopes cholesterol
2016/12/29
A high-carbohydrate, low-fat diet is recommended for the prevention of atherosclerosis, because it reduces plasma cholesterol concentrations. However, such a diet can increase plasma triacylglycerol c...
Hepatic de novo lipogenesis in normoinsulinemic and hyperinsulinemic subjects consuming high-fat, low-carbohydrate and low-fat, high-carbohydrate isoenergetic diets
docosahexaenoic acid DHA arachidonic acid
2016/12/27
Hypertriglyceridemia is associated with increased risk of cardiovascular disease. Until recently, the importance of hepatic de novo lipogenesis (DNL) in contributing to hypertriglyceridemia was diffic...
Effects of enteral carbohydrates on de novo lipogenesis in critically ill patients
Glucose production gluconeogenesis lipogenesis, insulin resistance enteral nutrition critically ill patients
2016/6/8
ABSTRACT
Background: Conversion of glucose into lipid (de novo lipogenesis;
DNL) is a possible fate of carbohydrate administered during
nutritional support. It cannot be detected by conventional me...