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Genetic risk for autism spectrum disorders and neuropsychiatric variation in the general population
Genetic risk autism spectrum disorders neuropsychiatric variation general population
2016/5/3
Almost all genetic risk factors for autism spectrum disorders (ASDs) can be found in the general population, but the effects of that risk are unclear in people not ascertained for neuropsychiatric sym...
Perhaps the central problem in understanding color appearance is that the only available measures are subjective. Much is now known about the neural mechanisms underlying the early encoding of color i...
Exome Sequencing in an Admixed Isolated Population Indicates NFXL1 Variants Confer a Risk for Specific Language Impairment
Exome Sequencing Admixed Isolated Population NFXL1 Variants Specific Language Impairment
2015/5/13
Children affected by Specific Language Impairment (SLI) fail to acquire age appropriate language skills despite adequate intelligence and opportunity. SLI is highly heritable, but the understanding of...
Detection of Runs of Homozygosity from Whole Exome Sequencing Data: State of the Art and Perspectives for Clinical, Population and Epidemiological Studies
Exome sequencing Runs of homozygosity Homozygosity mapping
2015/5/5
Runs of homozygosity (ROH) are sizeable stretches of homozygous genotypes at consecutive polymorphic DNA marker positions, traditionally captured by means of genome-wide single nucleotide polymorphism...
Population-level variability in the social climates of four chimpanzee societies
Social tolerance Chimpanzees Intraspecific variation Culture Norms Sharing Social networks
2015/5/5
Recent debates have questioned the extent to which culturally-transmitted norms drive behavioral variation in resource sharing across human populations. We shed new light on this discussion by examini...
The homozygosity index (HI) approach reveals high allele frequency for Wilson disease in the Sardinian population
Wilson disease genetic epidemiology consanguinity homozygosity index
2015/4/24
Wilson disease (WD) is an autosomal recessive disorder resulting in pathological progressive copper accumulation in liver and other tissues. The worldwide prevalence (P) is about 30/million, while in ...
Word class and context affect alpha-band oscillatory dynamics in an older population
lexical-semantic reading EEG oscillatory dynamics alpha theta
2015/4/21
Differences in the oscillatory EEG dynamics of reading open class (OC) and closed class (CC) words have previously been found (Bastiaansen et al., 2005) and are thought to reflect differences in lexic...
The imprint of the Slave Trade in an African American population: mitochondrial DNA, Y chromosome and HTLV-1 analysis in the Noir Marron of French Guiana
the Slave Trade African American population mitochondrial DNA Y chromosome HTLV-1 analysis Noir Marron French Guiana
2015/4/9
Background: Retracing the genetic histories of the descendant populations of the Slave Trade (16th-19th centuries) is particularly challenging due to the diversity of African ethnic groups involved an...
Population-based linkage analysis of schizophrenia and bipolar case–control cohorts identifies a potential susceptibility locus on 19q13
schizophrenia segmental sharing case–control genome scan
2015/4/8
Population-based linkage analysis is a new method for analysing genomewide single nucleotide polymorphism (SNP) genotype data in case–control samples, which does not assume a common disease, common va...
Explaining the Linguistic Diversity of Sahul Using Population Models
Linguistic Diversity Sahul Using Population Models
2015/4/7
The region of the ancient Sahul continent (present day Australia and New Guinea, and surrounding islands) is home to extreme linguistic diversity. Even apart from the huge Austronesian language family...
How Do Ukrainians Communicate?Observations Based upon Youth Population of Kyiv
communication patterns linguistic etiquette communicative competence Bohemian-Ukrainian contrasts cultural stereotypes particularism universalism individualism collectivism
2009/8/20
The paper examines communication patterns of contemporary Ukrainians, represented by a group of 18-30-year-old residents of Kyiv, the capital city. The methods of interview, participant-observation an...
An Examination of the Validity of English-Language Achievement Test Scores in an English Language Learner Population
English Language Learner Population achievement test
2008/9/16
Approximately 1,700 English language learners (ELLs) and former ELL students, in Grades 4 and 10, were tested using both an English-language (Stanford Achievement Test, 9th ed.) and a Spanish-language...