Urinary N-Acetyl-b-D-Glucosaminidase Excretion in Asphyctic Newborns-Does it Predict the Development of Acute Renal Failure?
[作者] Mete AKİ SÜ Nilgün KÜ LTÜ RSAY Resmiye ORAL Nermin TANSUĞ Caner KABASAKAL
[单位] Department of Pediatrics,Faculty of Medicine,Ege University,Bornova,İ zmir-Turkey Department of Pediatrics,SSK Hospital,Tepecik,İ zmir-Turkey
[摘要] Urinary N-acetyl-b-D-glucosaminidase (NAG) levels of twenty healthy full-term newborns and of seventeen full-term newborns with perinatal asphyxia were evaluated within the first 48 hours of life. Urinary NAG l…
[关键词] perinatal asphyxia urine kidney N-acetyl-b-D-glucosamindase
Urinary N-acetyl-b-D-glucosaminidase (NAG) levels of twenty healthy full-term newborns and of seventeen full-term newborns with perinatal asphyxia were evaluated within the first 48 hours of life. Urinary NAG levels and NAG indices (urinary NAG/urinary creatinine ratio) were sig-nificantly higher in newborns with perinatal asphyxia than control group (p<0.001). Four patients who developed an acute renal failure (ARF) had higher urinary NAG levels; but this increase was not found to be significant comparing to the NAG enzymuria in 13 other asphyctic newborns with normal renal functions. It is concluded that NAG enzymuria is an early sensitive indicator of proximal renal tubular damage and perinatal asphyxia but it does not predict the further deterioration in renal functions and the development of ARF.
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原文发布时间:2009/7/6
引用本文:
Mete AKİSÜ;Nilgün KÜLTÜRSAY;Resmiye ORAL;Nermin TANSUĞ;Caner KABASAKAL.Urinary N-Acetyl-b-D-Glucosaminidase Excretion in Asphyctic Newborns-Does it Predict the Development of Acute Renal Failure?.http://ynufe.firstlight.cn/View.aspx?infoid=736420&cb=nijuyanxg.
发布时间:2009/7/6.检索时间:2024/12/18